X Lan

Xi Lan, Ames, IA View Details

Cities: Sewickley PA, Towson MD

Xi Lan, Lynnwood, WA View Details

Cities: Sewickley PA, Towson MD

Xia Lan, Staten Island, NY View Details

Cities: Sewickley PA, Towson MD

X Lan, age 77 View Details

Address:***** Ringgold St, Haverhill, MA. Phone Number: (978) 618-****

X Lan View Details

Address:***** Scotts Manor Ct, Apt C, Odenton, MD. Phone Number: (410) 858-****

X Lan, age 60s View Details

X U Lan View Details

X I Lan, Towson, MD View Details

Locations: Towson MD, Baltimore MD

X Le Lan View Details

Possible Relatives: Anh Anh Le, Ba T Le, Duy Anh Le

X I Lan View Details

X I Lan View Details

X-linked agammaglobulinemia

X-linked agammaglobulinemia (XLA) is a rare genetic disorder discovered in 1952 that affects the body's ability to fight infection. As the form of agammaglobulinemia that is X-linked, it is much more read more...common in males. In people with XLA, the white blood cell formation process does not generate mature B cells, which manifests as a complete or near-complete lack of proteins called gamma globulins, including antibodies, in their bloodstream. B cells are part of the immune system and normally manufacture antibodies, which defend the body from infections by sustaining a humoral immunity response. Patients with untreated XLA are prone to develop serious and even fatal infections. A mutation occurs at the Bruton's tyrosine kinase (Btk) gene that leads to a severe block in B cell development and a reduced immunoglobulin production in the serum. Btk is particularly responsible for mediating B cell development and maturation through a signaling effect on the B cell receptor BCR. Patients typically present in early childhood with recurrent infections, in particular with extracellular, encapsulated bacteria. XLA is deemed to have a relatively low incidence of disease, with an occurrence rate of approximately 1 in 200,000 live births and a frequency of about 1 in 100,000 male newborns. It has no ethnic predisposition. XLA is treated by infusion of human antibody. Treatment with pooled gamma globulin cannot restore a functional population of B cells, but it is sufficient to reduce the severity and number of infections due to the passive immunity granted by the exogenous antibodies.read less...

X-Mansion

The X-Mansion or Xavier Institute is the common name for a mansion and research institute appearing in American comic books published by Marvel Comics. The mansion is depicted as the private estate ofread more... Charles Francis Xavier, a character in X-Men comics. It serves as the base of operations and training site of the X-Men. It is also the location of an accredited private school for mutant children, teenagers, and sometimes older aged mutants, the Xavier Institute for Higher Learning, formerly the Xavier School for Gifted Youngsters. The X-Mansion is also the worldwide headquarters of the X-Corporation.read less...

X-linked ichthyosis

X-linked ichthyosis is a skin condition caused by the hereditary deficiency of the steroid sulfatase (STS) enzyme that affects 1 in 2000 to 1 in 6000 males. XLI manifests with dry, scaly skin and is dread more...ue to deletions or mutations in the STS gene. XLI can also occur in the context of larger deletions causing contiguous gene syndromes. Treatment is largely aimed at alleviating the skin symptoms. The term is from the Ancient Greek 'ichthys' meaning 'fish'.read less...

X-linked dystonia parkinsonism

X-linked dystonia parkinsonism (XDP), also known as Lubag Syndrome or X-linked Dystonia of Panay, is a rare x-linked progressive movement disorder with high penetrance found almost exclusively in maleread more...s from Panay, Philippines. It is characterized by dystonic movements first typically occurring in the 3rd and 4th decade of life. The dystonic movements often either coexist or develop into parkinsonism within 10 years of disease onset.read less...

X-linked dominant inheritance

X-linked dominant inheritance, sometimes referred to as X-linked dominance, is a mode of genetic inheritance by which a dominant gene is carried on the X chromosome. As an inheritance pattern, it is lread more...ess common than the X-linked recessive type. In medicine, X-linked dominant inheritance indicates that a gene responsible for a genetic disorder is located on the X chromosome, and only one copy of the allele is sufficient to cause the disorder when inherited from a parent who has the disorder. In this case, someone who expresses an X-linked dominant allele will exhibit the disorder and be considered affected.read less...

X-linked spinal muscular atrophy type 2

X-linked spinal muscular atrophy type 2, also known as arthrogryposis multiplex congenita X-linked type 1 (AMCX1), is a rare neurological disorder involving death of motor neurons in the anterior hornread more... of spinal cord resulting in generalised muscle wasting (atrophy). The disease is caused by a mutation in UBA1 gene and is passed in an X-linked recessive manner by carrier mothers to affected sons.read less...