Ian Trace

I Tracey, age 30s, Streetsboro, OH View Details

Locations: Streetsboro OH, Broadview Heights OH, Cleveland OH Possible Relatives: John Frank Dudinsky, Brianna F Heisler, Cathleen Mary Tracey

Ian E Trace, age 70s, Hendersonville, NC View Details

Locations: Hendersonville NC, Lehigh Acres FL

Ian Ernest edward Trace, age 70s, Columbus, NC View Details

Locations: Columbus NC, Hendersonville NC, Mountain Home NC Possible Relatives: Brenda B Kuhlman, Kimberly A Moller, Tami Lyn Summey

Ian E Trace, Columbus, NC View Details

Locations: Columbus NC, Hendersonville NC, Mountain Home NC Possible Relatives: Brenda B Kuhlman, Kimberly A Moller, Tami Lyn Summey

Ian Trace, Mountain Home, NC View Details

Cities: Mountain Home NC

Ian Trace, Mountain Home, NC View Details

Locations: Mountain Home NC

Intracellular pH

Intracellular pH (pHi) is the measure of the acidity or basicity of intracellular fluid. The pHi plays a critical role in membrane transport and other intracellular processes. In an environment with tread more...he improper pHi, biological cells may have compromised function. Therefore, pHi is closely regulated in order to ensure proper cellular function, controlled cell growth, and normal cellular processes. The mechanisms that regulate pHi are usually considered to be plasma membrane transporters of which two main types exist — those that are dependent and those that are independent of the concentration of bicarbonate. Physiologically normal intracellular pH is most commonly between 7.0 and 7.4, though there is variability between tissues. There is also pH variation across different organelles, which can span from around 4.5 to 8.0. pHi can be measured in a number of different ways.read less...

Intracellular transport

Intracellular transport is the movement of vesicles and substances within a cell. Intracellular transport is required for maintaining homeostasis within the cell by responding to physiological signalsread more.... Proteins synthesized in the cytosol are distributed to their respective organelles, according to their specific amino acid’s sorting sequence. Eukaryotic cells transport packets of components to particular intracellular locations by attaching them to molecular motors that haul them along microtubules and actin filaments. Since intracellular transport heavily relies on microtubules for movement, the components of the cytoskeleton play a vital role in trafficking vesicles between organelles and the plasma membrane by providing mechanical support. Through this pathway, it is possible to facilitate the movement of essential molecules such as membrane‐bounded vesicles and organelles, mRNA, and chromosomes.read less...

Intracellular digestion

Every organism requires energy to be active. However, to obtain energy from its outside environment, cells must not only retrieve molecules from their surroundings but also break them down. This proceread more...ss is known as intracellular digestion. In its broadest sense, intracellular digestion is the breakdown of substances within the cytoplasm of a cell. In detail, a phagocyte's duty is obtaining food particles and digesting it in a vacuole. For example, following phagocytosis, the ingested particle fuses with a lysosome containing hydrolytic enzymes to form a phagolysosome; the pathogens or food particles within the phagosome are then digested by the lysosome's enzymes.read less...

Intracellular receptor

Intracellular receptors are receptors located inside the cell rather than on its cell membrane. Classic hormones that use intracellular receptors include thyroid and steroid hormones. Examples are theread more... class of nuclear receptors located in the cell nucleus and cytoplasm and the IP3 receptor located on the endoplasmic reticulum. The ligands that bind to them are usually intracellular second messengers like inositol trisphosphate (IP3) and extracellular lipophilic hormones like steroid hormones. Some intracrine peptide hormones also have intracellular receptors.read less...

Intracerebroventricular injection

Intracerebroventricular injection is an invasive injection technique of substances directly into the cerebrospinal fluid in cerebral ventricles in order to bypass the blood brain barrier. Although thiread more...s barrier effectively protects the brain, it can prevent important medications from entering the CNS. The technique is widely used in biomedical research to introduce drugs, therapeutic RNAs, plasmid DNAs, and viral vectors into the CNS of diseased mice models. It can also be used in human in cases of neurodegenerative disorders like spinal muscular atrophy (SMA), or administering chemotherapy in gliomas as well as delivering neurotrophic factors to CNS. It can be contrasted with intraperitoneal injection as an alternative choice of route of administration with differing pharmacokinetic and pharmacodynamic effects.read less...

Intracellular antibody-mediated degradation

Intracellular antibody-mediated degradation (IAMD) is a neutralization mechanism of intracellular antibody-mediated immunity whereby an effector protein, TRIM21, directs antibody bound virions to the read more...proteasome where they are degraded. As yet, it has only been observed to act against the adenovirus but is likely to also be effective against other non-enveloped viruses.read less...