Eric Ptoe

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Eric Ptoe's address is ***** Lafitte Dr, Hubert, NC.

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Eric Ptoe's age is 54.

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Eric Ptoe's phone number is (910) 389-****.

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Eric Murnane Poeschla is an American infectious disease physician, virologist and immunologist. After graduating from the Yale School of Medicine he completed his residency in internal medicine at the University of California, San Francisco School of Medicine in 1988, followed by a year of tropical medicine training and practice in the highlands of Papua New Guinea. He was the project physician for the 1990 Vanderbilt University Petexbatun Region Maya Archaeology Expedition in Dos Pilas, Guatemala. He did an infectious disease fellowship and post-doctoral training in virology at the University of California, San Diego School of Medicine, and was then recruited to Mayo Clinic College of Medicine in 1999, where he was Professor of Molecular Medicine and directed virology research focused on the HIV life cycle. He is interested in how viruses interact with, use, or evade cellular proteins as they replicate, as well as innate immunity, and viral emergence. Early work determined how FIV, the feline HIV-like virus, can or cannot execute its life cycle steps in cells of different species; the work also established the first FIV-based lentiviral vector system. Subsequent research included contributions to identifying the role of a cellular protein (LEDGF) in the chromosomal attachment and integration step of HIV, and investigations of other cellular factors that regulate the HIV life cycle. More recent studies have further concerned cellular innate immune defenses to other RNA viruses. The laboratory uses picornavirus RNA polymerase-transgenic mouse models to investigate Interferon-stimulated gene (ISG) responses triggered by viral double-stranded RNA via the sensor MDA5. The mice have lifelong elevations of many ISGs and resist normally lethal challenges by numerous RNA and DNA viruses. However, they lack expected auto-inflammatory tradeoffs of chronic MDA5 activation and this unusual avoidance of autoimmunity or 'interferonopathy' is a main question of interest. In 2020, his laboratory and colleagues in Singapore described a restriction, or block, to primate lentiviruses in cells of large (Pteropid) bats. Since 2014, Poeschla has been Professor of Medicine and Chief of the Infectious Diseases Division at the University of Colorado School of Medicine, where he also holds the Tim Gill Endowed Chair in HIV Research and has helped direct the institutional response to the COVID-19 pandemic. Poeschla was elected to the Association of American Physicians (AAP) in 2016. He lives in Denver.. You can find more here.

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