Epstein

Ann Epstein, age 105, Mahopac, NY View Details

Cities: Mahopac NY, Tucson AZ Possible Relatives: Ann Epstein

Alan Carole Epstein, age 75, Armonk, NY View Details

Cities: Armonk NY, Pryor OK, Mount Kisco NY Possible Relatives: Carole R Epstein, Dara H Epstein, Mathew E Epstein

Alfred L Epstein, age 75, Bronx, NY View Details

Cities: Bronx NY Possible Relatives: Alfred Leo Epstein, Jenny G Epstein, Leo Alfred Epstein

Alison J Epstein, age 49, New York, NY View Details

Cities: New York NY Possible Relatives: Alison Epstein, Jennifer Cari Epstein, Linda E Epstein

Albert Epstein, age 103, Boynton Beach, FL View Details

Cities: Boynton Beach FL, Flushing NY Possible Relatives: Philip Dominic Epstein, Savina Epstein

Alvin Epstein, age 54, Delray Beach, FL View Details

Cities: Delray Beach FL, Henderson NV Possible Relatives: Arlene Epstein

Adam Xavier Epstein, age 43, Newport News, VA View Details

Cities: Newport News VA, Hampton VA Possible Relatives: Lindsay Nicole Bessette, Brian I Epstein, Eve L Epstein

Lester Alan Epstein, age 65, Peoria, AZ View Details

Locations: Birmingham AL, Mountain Brook AL, Madeira Beach FL

Caren Brooke Epstein, age 63, Weimar, TX View Details

Locations: Birmingham AL, Mountain Brook AL, Madeira Beach FL Possible Relatives: Ami E Abel, Ki Lynn Abel

Marc I Epstein, age 62, Tucson, AZ View Details

Locations: Birmingham AL, Mountain Brook AL, Madeira Beach FL Possible Relatives: Ami E Abel, Ki Lynn Abel

Lisa Jane Epstein, age 57, Paradise Valley, AZ View Details

Locations: Birmingham AL, Mountain Brook AL, Madeira Beach FL Possible Relatives: Ami E Abel, Ki Lynn Abel

Elliott B Epstein, age 53, Juneau, AK View Details

Locations: Birmingham AL, Mountain Brook AL, Madeira Beach FL Possible Relatives: Ami E Abel, Ki Lynn Abel

Ami A Martinez, age 48, Mountain Brk, AL View Details

Locations: Birmingham AL, Mountain Brook AL, Madeira Beach FL Possible Relatives: Ami E Abel, Ki Lynn Abel

Lee Gabrielle Silva, age 43, San Antonio, TX View Details

Locations: Birmingham AL, Mountain Brook AL, Madeira Beach FL Possible Relatives: Ami E Abel, Ki Lynn Abel

Epstein–Barr virus infection

There are several forms of Epstein–Barr virus (EBV) infection. These include asymptomatic infections, the primary infection, infectious mononucleosis, and the progression of asymptomatic or primary read more...infections to: 1) any one of various Epstein-Barr virus-associated lymphoproliferative diseases such as chronic active EBV infection, EBV+ hemophagocytic lymphohistiocytosis, Burkitt's lymphoma, and Epstein Barr virus positive diffuse large B-cell lymphoma, not otherwise specified); 2) non-lymphoid cancers such as Epstein-Barr virus associated gastric cancer, soft tissue sarcomas, leiomyosarcoma, and nasopharyngeal cancers; and 3) Epstein-Barr virus-associated non-lymphoproliferative diseases such as some cases of the immune disorders of multiple sclerosis and systemic lupus erythematosis and the childhood disorders of Alice in Wonderland Syndrome and acute cerebellar ataxia.read less...

Epstein syndrome

Epstein syndrome is a rare genetic disease characterized by a mutation in the MYH9 gene in nonmuscle myosin. This disease affects the patient's renal system and can result in kidney failure. Epstein Sread more...yndrome was first discovered in 1972 when two families had similar symptoms to Alport syndrome. Epstein syndrome and other Alport-like disorders were seen to be caused by mutations in the MYH9 gene, however, Epstein syndrome differs as it was more specifically linked to a mutation on the R702 codon on the MYH9 gene. Diseases with mutations on the MYH9 gene also include May–Hegglin anomaly, Sebastian syndrome and Fechtner syndrome.read less...

Epstein–Barr virus nuclear antigen 1

Epstein–Barr nuclear antigen 1 (EBNA1) is a multifunctional, dimeric viral protein associated with Epstein–Barr virus (EBV). It is the only EBV protein found in all EBV-related malignancies. It isread more... important in establishing and maintaining the altered state that cells take when infected with EBV. EBNA1 has a glycine–alanine repeat sequence that separates the protein into amino- and carboxy-terminal domains. This sequence also seems to stabilize the protein, preventing proteasomal breakdown, as well as impairing antigen processing and MHC class I-restricted antigen presentation. This thereby inhibits the CD8-restricted cytotoxic T cell response against virus-infected cells. EBNA1 is expressed from the Qp promoter during all latency programs. It is the only viral protein expressed in latency program I.read less...

Epstein–Barr virus stable intronic-sequence RNAs

Epstein–Barr virus stable intronic-sequence RNAs (ebv-sisRNAs) are a class of non-coding RNAs generated by repeat introns in the Epstein–Barr virus. After EBERs 1 and 2, ebv-sisRNA-1 is the third read more...most abundant EBV RNA generated during a highly oncogenic form of virus latency. Conservation of ebv-sisRNA sequence and secondary structure between EBV and other herpesviruses suggest shared functions in latent infection.read less...

Epstein–Barr virus latent membrane protein 2

Epstein–Barr virus (EBV) latent membrane protein 2 (LMP2) are two viral proteins of the Epstein–Barr virus. LMP2A/LMP2B are transmembrane proteins that act to block tyrosine kinase signaling. LMP2read more...A is a transmembrane protein that inhibits normal B-cell signal transduction by mimicking an activated B-cell receptor (BCR). The N-terminus domain of LMP2A is tyrosine phosphorylated and associates with Src family protein tyrosine kinases (PTKs) as well as spleen tyrosine kinase (Syk). PTKs and Syk are associated with BCR signal transduction.read less...

Epstein–Barr virus vaccine

As of 2021 a vaccine against Epstein–Barr virus was not yet available. The virus establishes latent infection and causes infectious mononucleosis. It is a dual-tropic virus, causing infection of botread more...h B cells and epithelial cells. One challenge is that the Epstein–Barr virus expresses very different proteins during its lytic and its latent phases. Antiviral agents act by inhibiting viral DNA replication, but as of 2016 there was little evidence that they are effective against Epstein–Barr virus, they are expensive, they risk causing resistance to antiviral agents, and can cause unpleasant side effects.read less...