Also known as: brettpearsall
Brett Pearsall lives in San Diego, California.
Also known as: BBrett_01
I love God, the Dodgers, Steelers, Lakers, Pens and of course Rachael Weathers .Proud SDSU Aztec
Also known as: _Brett_B
I am a Senior Scientist level Medicinal Chemists with years experience at the design and synthesis of small molecule drug compounds. I am active in lab carrying out multi-step organic synthesis, compound isolation, and analytical characterization. I have experience optimizing lead compounds through SAR for improved potency, selectivity, PK, and ADME properties. I have synthesized potent small molecule modulators of nuclear hormone receptors, GPCR's, and protein kinases. Specific experiences includes Drug discovery in the areas of oncology, cardiovascular and metabolic disease Structure-Based Drug Design Chemistry project leader responsible for planning and implementing drug discovery program overseeing direct reports and CRO FTE's Inventor of the commercial compound XCT, the leading synthetic ERRa antagonist Co-inventor of LXR clinical candidates XL (BMS) and XL(BMS), investigational drugs to treat atherosclerosis Co-inventor of XL, a FXR agonist clinical candidate Developed multi-step synthetic procedures applicable to CMC scale-up production Multidisciplinary interaction with Biology, Lead Discovery, IT, CRO, CMC, and Pharma collaborators Co-inventor of polyhomologation methodology, a living polymerization using sulfur ylides and organoborane reagents Hands on application of modern analytical techniques including H NMR, C NMR, LCMS, GCMS, X-ray diffraction Fragment Based Drug Design ... ... Specialties Chemist Research Scientist Research Chemist Medicinal Chemist Structure Based Drug Design Organic Chemist Fragment Based Drug Methods Organic Synthesis Rational Drug Design Polymer Monomer Synthesis Compound Isolation Purification Analytical Characterization (NMR, LCMS, GCMS) Lab Management Patent Writing Intellectual Property CRO Management Outsourcing Specialist Organic Chemistry
Also known as: bbettesworth
To use my diverse background in business, law, and policy to bring enthusiasm and excellence to a lively and innovative organization. Specialties Billing, customer relations, customer service, inventory management, legal, meeting facilitation, presentation skills, research, sales, seminars, spreadsheets, strategic development
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Brett Ratner (born March 28, 1969) is an American director and producer.He is known for directing the Rush Hour film series, The Family Man, Red Dragon, X-Men: The Last Stand, and Tower Heist.He was also a producer of the films Black Mass, The …. You can find more here.
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